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Public outreach

Publication

Antranikian, G. and Streit, W.R. (2022) Microorganisms harbor keys to a circular bioeconomy making them useful tools in fighting plastic pollution and rising CO2 levels. Extrem. 2022 261 26: 1–11. doi: 10.1007/S00792-022-01261-4


Publication

Zhang, H., Perez-Garcia, P., Dierkes, R.F., Applegate, V., Schumacher, J., Chibani, C.M., et al. (2022) The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity. Front. Microbiol. 12: 3874. doi: 10.3389/fmicb.2021.803896


Publication

Buchholz, P.C.F., Feuerriegel, G., Zhang, H., Perez‐Garcia, P., Nover, L.-L., Chow, J., et al. (2022) Plastics degradation by hydrolytic enzymes: The plastics‐active enzymes database—PAZyProteins Struct. Funct. Bioinforma. https://doi.org/10.1002/prot.26325


Publication

El Harrar, T., Frieg, B., Davari, M.D., Jaeger, K.E., Schwaneberg, U., and Gohlke, H. (2021) Aqueous ionic liquids redistribute local enzyme stability via long-range perturbation pathways. Comput. Struct. Biotechnol. J. 19: 4248–4264. doi:10.1016/J.CSBJ.2021.07.001


Publication

Perez-Garcia, P., Kobus, S., Gertzen, C.G.W., Hoeppner, A., Holzscheck, N., Strunk, C.H., et al. (2021) A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family. Commun. Biol. 2021 41 4: 1–12. doi:10.1038/s42003-021-01671-8


Publication

Harrar, T. El, Davari, M.D., Jaeger, K.-E., Schwaneberg, U., and Gohlke, H. (2021) Critical assessment of structure-based approaches to improve protein resistance in aqueous ionic liquids by enzyme-wide saturation mutagenesis. Comput. Struct. Biotechnol. J. doi:10.1016/j.csbj.2021.12.018


Publication

Höppner A, Bollinger A, Kobus S, Thies S, Coscolín C, Ferrer M, Jaeger K-E, Smits SHJ. Crystal structures of a novel family IV esterase in free and substrate‐bound form. FEBS J; 2021;. 288: 3570–3584. doi:10.1111/febs.15680


Publication

Nutschel, C., Coscolín, C., David, B., Mulnaes, D., Ferrer, M., Jaeger, K.-E., and Gohlke, H. (2021) Promiscuous Esterases Counterintuitively Are Less Flexible than Specific Ones. J. Chem. Inf. Model. 61: 2383–2395. doi: 10.1021/acs.jcim.1c00152


Publication

Cui, H., Eltoukhy, L., Zhang, L., Markel, U., Jaeger, K.E., Davari, M.D., and Schwaneberg, U. (2021) Less Unfavorable Salt Bridges on the Enzyme Surface Result in More Organic Cosolvent Resistance. Angew. Chemie - Int. Ed. 60: 11448–11456. doi: 10.1002/anie.202101642


Blog-Entry

Molitor R

Blaue Biotechnologie – Eine Expedition zum Nordatlantischen Müllstrudel

JülichBlog Bioökonomie

https://blogs.fz-juelich.de/biooekonomie/2021/03/01/blaue-biotechnologie-eine-expedition-zum-nordatlantischen-muellstrudel/


Publikation

Perez-Garcia P, Kobus S, Gertzen CGW, Hoeppner A, Holzscheck N, Strunk CH, Huber H, Jaeger K-E, Gohlke H, Kovacic F, Smits SHJ, Streit W, Chow J. (2021). A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family. Commun Biol. 2021;4: 132. doi:10.1038/s42003-021-01671-8


Publication:
Höppner A, Bollinger A, Kobus S, Thies S, Coscolín C, Ferrer M, Jaeger K-E, Smits SHJ. Crystal structures of a novel family IV esterase in free and substrate‐bound form. FEBS J; 2020; febs.15680. doi:10.1111/febs.15680


Publication
Bollinger A, Molitor R, Thies S, Koch R, Coscolín C, Ferrer M, Jaeger K-E (2020) Organic-Solvent-Tolerant Carboxylic Ester Hydrolases for Organic Synthesis. Appl Environ Microbiol 86:e00106-20 . https://doi.org/10.1128/AEM.00106-20


Newspaper article
Forschung in Düsseldorf: So sollen die Meere sauber werden
https://rp-online.de/nrw/staedte/duesseldorf/duesseldorf-bakterien-sollen-das-meer-reinigen_aid-49560371


Publication
Bollinger A, Thies S, Knieps-Grünhagen E, Gertzen C, Kobus S, Höppner A, Ferrer M, Gohlke H, Smits SHJ, Jaeger K-E (2020) A Novel Polyester Hydrolase From the Marine Bacterium Pseudomonas aestusnigri – Structural and Functional Insights. Front Microbiol 11:114 . https://doi.org/10.3389/fmicb.2020.00114


Press release
Vier neue Projekte zur Bioökonomie an der HHU

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